Top-down factors are components of the neuroendocrine system. These factors play a supervisory role in regulating energy systems that are necessary for meeting the high energy demands of the brain.
Thyroid hormones are at the top of the list for two good reasons, 1) they play the most direct role in regulating basal metabolic rate, and 2) the standard of care for hypothyroid symptoms is woefully dysfunctional.
Welcome to the medical side of Alzheimer’s disease reversal. Start here.
I’ll be doing two series of posts about reversing Alzheimer’s, one for medical professionals and scientists, and another for lay readers. The first one should be relatively comprehensive, and the second should be simple and straightforward.